Nuclear war and malicious use of AI could end humanity by 2100, scientists warn

By Jonathan Benton, 12/10/2026 , https://www.euronews.com/2026/10/12/nuclear-war-and-malicious-use-of-ai-could-end-humanity-by-2100-scientists-warn
They are among 17 global threats to human health according to a new study by The Lancet which aims to drive global action to address them.
The malicious use of AI or nuclear war could end humanity as we know it by 2100, according to a new global health risk assessment.
They top a pyramid of 17 major threats to human health identified in a study published in The Lancet, including antimicrobial resistance, climate change, pandemics, income inequality and a range of health issues such as tobacco, obesity and mental health.
According to the study, nuclear conflict does not just cover the impact of the missiles but the consequences too, such as nuclear famine, while the malicious use of AI includes the use and development of bioweapons against us.
The research was conducted by the new Lancet Commission on 21st-century global threats to health, a group made up of 37 experts in health, economics, security and technology.
Together they used disability-adjusted life years, also known DALYs, as a metric to compare each threat from the year 2025 to 2100 from 204 countries and territories across age, sex and cause.
The research essentially shows how many healthy years of human life could be lost to each global threat, according to their best- and worst-case scenarios. This also gives an idea of how much of an impact humanity can have if it acts now or chooses to do nothing.
Together they used disability-adjusted life years, also known DALYs, as a metric to compare each threat from the year 2025 to 2100 from 204 countries and territories across age, sex and cause.
The research essentially shows how many healthy years of human life could be lost to each global threat, according to their best- and worst-case scenarios. This also gives an idea of how much of an impact humanity can have if it acts now or chooses to do nothing.
They also call for more investment in “breakthrough solutions,” such as nuclear fusion and carbon removal technologies that could radically affect climate change outcomes and other globally threatening issues, or the vaccines developed during the pandemic.
The Commission also calls for regular monitoring and risks assessments of these risks, with findings presented to international organisations such as the G20 and the UN to increase the urgency in addressing the issues before they escalate and become crises, and encourage wider action rather than individual countries going it alone.
Researchers believe the current “competitive approach” of tackling major challenges one by one is hindering humanity’s chances.
The Commission’s findings were presented on Sunday at the World Health Summit in Berlin, Germany. Their assessment will be updated each year to re-evaluate each of the 17 threats identified, incorporating new data and any emerging challenges.
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