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Why should you care about ‘specks’ of plutonium? Hanford health challenge

 

12951_2004_Article_18_Fig4_HTML
Figure 4

Translocation of inhaled ultrafine particles. Time-activity curve over liver and bladder expressed as percent of initial lung radioactivity. Insert, Whole body gamma camera image of 1 representative volunteer recorded at 60 minutes. The radioactivity over the organs is expressed as counts per minute (CPM) per pixel within each region of interest (ROI). The values recorded over the stomach were not included because this radioactivity may also come partly from swallowing of particles deposited in the mouth. Reproduced with permission from Nemmar et al, “Passage of inhaled particles into the blood circulation in humans”, Circulation 2002;105(4):411-41.

 

Hanford Challenge

Why should you care about ‘specks’ of plutonium?

Even Hanford’s internal reports challenge DOE’s assumption that specks stay in the body for one year. According to one report, high-fired oxide plutonium that PFP handled stays in the body for 10,000 days (i.e. over 27 years).

Why does 10,000 days matter?

Well, the longer the ‘speck’ stays in the human body, the more time it has to cause harm. If a worker was exposed to the high-fired plutonium oxides, the doses to these workers could be 27 times higher than DOE has assumed. (i.e. not good).

So, we must ask: Has DOE measured these particles from PFP and determined whether they are high-fired oxides? Or are they simply assuming? If assuming, what justifies this assumption?

Report excerpt: “retention half-lives for the transport from the lung to the blood have been adjusted from 500 days to 10,000 days [ 27.4 years], representing the highly insoluble (i.e., very slow dissolution rate) of the super class Y material. The precise nature of super class Y material is not known, although it appears to have been associated with processes involving high-fired plutonium oxides … Super class Y is not routinely used as a default program design form.”

Source: https://goo.gl/5QCA25

More here;

Nanoparticles for drug delivery to the brain is a method for transporting drug molecules across the blood–brain barrier (BBB) using nanoparticles. … Other biological factors influence how drugs are transported throughout the body and how they target specific locations for action.

Blood-brain_barrier_transport_en

This diagram shows several ways in which transport across the BBB works. For nanoparticle delivery across the BBB, the most common mechanisms are receptor-mediated transcytosis and adsorptive transcytosis

https://en.wikipedia.org/wiki/Nanoparticles_for_drug_delivery_to_the_brain

And this;

These fibres are often described as being in the “interstitial” where they may lie between or within the cells making up the alveolar walls. Bio-persistent solid materials, certainly those particles containing mutagenic substances or asbestos fibres or silica, which remain for years in the lungs, increase the risk of developing cancer.

https://jnanobiotechnology.biomedcentral.com/articles/10.1186/1477-3155-2-12

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February 2, 2018 - Posted by | Uncategorized

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